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Yusuke Nakamura Selected Research

Protein Subunit Vaccines

1/2022Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects.
9/2018Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.
1/2018WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia.
11/2017miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
5/2017Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
1/2017Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer.
1/2017A Pilot Study of Post-Operative Adjuvant Vaccine for Advanced Gastric Cancer.
1/2017Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study.
6/2016Characterization of the T cell repertoire by deep T cell receptor sequencing in tissues and blood from patients with advanced colorectal cancer.
1/2015Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
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Yusuke Nakamura Research Topics

Disease

309Neoplasms (Cancer)
07/2022 - 01/2002
83Carcinogenesis
11/2020 - 08/2002
70Breast Neoplasms (Breast Cancer)
05/2022 - 01/2002
51Lung Neoplasms (Lung Cancer)
01/2022 - 04/2003
33Colorectal Neoplasms (Colorectal Cancer)
11/2021 - 03/2002
23Pancreatic Neoplasms (Pancreatic Cancer)
01/2018 - 03/2004
22Testicular Neoplasms (Testicular Cancer)
05/2017 - 08/2004
19Prostatic Neoplasms (Prostate Cancer)
03/2022 - 12/2003
18Urinary Bladder Neoplasms (Bladder Cancer)
11/2018 - 04/2005
17Carcinoma (Carcinomatosis)
07/2022 - 08/2002
17Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2022 - 07/2003
17Adenocarcinoma
12/2017 - 06/2002
16Asthma (Bronchial Asthma)
01/2019 - 06/2005
15Esophageal Neoplasms (Esophageal Cancer)
01/2022 - 10/2004
15Stomach Neoplasms (Stomach Cancer)
08/2020 - 12/2002
15Infections
01/2013 - 05/2003
14Renal Cell Carcinoma (Grawitz Tumor)
01/2017 - 06/2005
14Chronic Hepatitis C
05/2013 - 05/2009
13Neoplasm Metastasis (Metastasis)
05/2022 - 02/2004
13Squamous Cell Carcinoma of Head and Neck
01/2021 - 01/2015
13Hepatocellular Carcinoma (Hepatoma)
03/2018 - 06/2002
13Rheumatoid Arthritis
07/2013 - 08/2003
12Ovarian Neoplasms (Ovarian Cancer)
07/2021 - 11/2007
11Colonic Neoplasms (Colon Cancer)
06/2020 - 03/2002
11Drug-Related Side Effects and Adverse Reactions
03/2012 - 01/2005
10Adenocarcinoma of Lung
03/2019 - 06/2002
9Synovial Sarcoma (Synovioma)
02/2022 - 10/2002
9Inflammation (Inflammations)
01/2019 - 12/2003
9Obesity
11/2010 - 01/2004
8Residual Neoplasm
09/2021 - 04/2014
8Leukemia
01/2018 - 04/2003
8Disease Susceptibility (Diathesis)
01/2013 - 01/2002
7Autoimmune Diseases (Autoimmune Disease)
07/2018 - 07/2008
7Type 2 Diabetes Mellitus (MODY)
07/2013 - 01/2005
6Melanoma (Melanoma, Malignant)
12/2021 - 12/2004
6Inborn Genetic Diseases (Disease, Hereditary)
01/2021 - 01/2002
6Hypoxia (Hypoxemia)
11/2020 - 06/2005

Drug/Important Bio-Agent (IBA)

120Proteins (Proteins, Gene)FDA Link
05/2022 - 10/2002
112Complementary DNA (cDNA)IBA
01/2015 - 01/2002
65Peptides (Polypeptides)IBA
07/2022 - 12/2002
59Small Interfering RNA (siRNA)IBA
02/2020 - 05/2004
56AntigensIBA
05/2022 - 08/2004
48Biomarkers (Surrogate Marker)IBA
02/2020 - 08/2006
41Pharmaceutical PreparationsIBA
09/2021 - 01/2002
25DNA (Deoxyribonucleic Acid)IBA
09/2021 - 01/2002
25EpitopesIBA
08/2021 - 01/2004
23T-Cell Antigen Receptors (T-Cell Receptor)IBA
07/2022 - 12/2004
23Messenger RNA (mRNA)IBA
11/2020 - 01/2002
22Phosphotransferases (Kinase)IBA
09/2021 - 04/2005
21EnzymesIBA
12/2020 - 08/2003
19HLA-A Antigens (HLA-A)IBA
05/2018 - 12/2004
18Biological ProductsIBA
08/2020 - 11/2004
18TamoxifenFDA LinkGeneric
01/2019 - 01/2007
17Protein Subunit VaccinesIBA
01/2022 - 11/2008
17Cancer VaccinesIBA
01/2022 - 05/2006
17InterferonsIBA
01/2018 - 05/2009
16Tumor Biomarkers (Tumor Markers)IBA
05/2022 - 08/2002
16Protein Kinases (Protein Kinase)IBA
12/2021 - 09/2003
16Histones (Histone)IBA
10/2020 - 10/2004
15VaccinesIBA
07/2022 - 11/2008
13Carrier Proteins (Binding Protein)IBA
02/2020 - 01/2005
12HLA Antigens (Human Leukocyte Antigens)IBA
01/2022 - 02/2009
12Lysine (L-Lysine)FDA Link
10/2020 - 02/2011
11Immune Checkpoint InhibitorsIBA
07/2022 - 01/2016
11Estrogen ReceptorsIBA
05/2022 - 10/2004
11Hormones (Hormone)IBA
04/2020 - 06/2007
11Cytochrome P-450 CYP2D6 (CYP2D6)IBA
01/2017 - 05/2008
11Histone MethyltransferasesIBA
10/2015 - 08/2004
11Ribavirin (Virazole)FDA LinkGeneric
01/2012 - 09/2010
10GemcitabineFDA Link
11/2018 - 04/2003
10CytokinesIBA
12/2017 - 12/2003
9Circulating Tumor DNAIBA
05/2022 - 07/2019
9beta CateninIBA
07/2010 - 01/2002
8OTS167IBA
11/2020 - 12/2014
8Transcription Factors (Transcription Factor)IBA
01/2020 - 01/2002
8Oncogene Proteins (Oncogene Protein)IBA
01/2018 - 11/2004
8Insulin-Like Growth Factor II (Somatomedin A)IBA
07/2017 - 01/2007
8Genetic Markers (Genetic Marker)IBA
02/2013 - 01/2009
7Amino AcidsFDA Link
11/2019 - 05/2004
7Cadherins (E-Cadherin)IBA
01/2016 - 04/2005
7Histone DemethylasesIBA
07/2015 - 03/2010
7Indicators and Reagents (Reagents)IBA
02/2013 - 01/2002
6Neoplasm Antigens (Tumor Antigens)IBA
07/2022 - 10/2004
6ErbB Receptors (EGF Receptor)IBA
05/2022 - 07/2003
6Cell-Free Nucleic AcidsIBA
05/2022 - 01/2020
6RNA (Ribonucleic Acid)IBA
01/2021 - 01/2007
6Estrogens (Estrogen)FDA Link
11/2020 - 08/2009
6AntibodiesIBA
09/2020 - 12/2004
6Glycoproteins (Glycoprotein)IBA
02/2020 - 09/2007
6LectinsIBA
02/2020 - 01/2005
6OligonucleotidesIBA
01/2020 - 06/2002
6Protein MethyltransferasesIBA
11/2018 - 08/2015
6Glucose (Dextrose)FDA LinkGeneric
01/2017 - 01/2008

Therapy/Procedure

148Therapeutics
07/2022 - 08/2002
41Immunotherapy
05/2022 - 08/2004
40Drug Therapy (Chemotherapy)
01/2022 - 01/2002
27Lasers (Laser)
11/2017 - 06/2002
9Radiotherapy
09/2021 - 07/2002
8Neoadjuvant Therapy
11/2018 - 03/2004
7Precision Medicine
09/2021 - 07/2010